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r9k / / steam / Where to Go if 8chan Goes Down / Nostalgia Thread Archive /

File: 1458446433012.jpg (10.63 KB, 235x255, 47:51, 1458278865077-2.jpg)

 No.172385

Greenpill/redpill me on antidepressants.

 No.172395

File: 1458446795995.jpg (99.45 KB, 483x316, 483:316, recreational drug use enth….jpg)

I legit think american doctors are compensated for prescribing them. I was offered a prescription for anti-depressants for a completely unrelated issue and the doctor came on suspiciously strong in their recommendation.


 No.172401

File: 1458446942217.jpg (45.06 KB, 447x489, 149:163, woke.jpg)

ssris are dewoking agents


 No.172402

>>172400

>tfw no insurance

>tfw one misstep away from complete financial ruin

smh


 No.172405

http://www.nejm.org/doi/full/10.1056/NEJMsa065779

antidepressants are l*terally useless

Ketamine + weight lifting + vitamin d3 (in winter time) should help


 No.172411

File: 1458447445163.jpg (45.39 KB, 590x446, 295:223, careful.jpg)

>>172408

>you shouldn't give basic advice because a few damb redarts might hurt themselves


 No.172417

>>172408

I agree with that poster in part, you don't even have to go outside to exercise, family, let alone sign up for a gym or whatever. Obese people should be responsible and know what their limits are. Walking around their home past exhaustion and doing remedial body weight exercises could prove highly beneficial.

>tfw no creative, protein, cool shades, dumbbells etc. flag

Tangent: Should I just give the flags to gipetto of forechan?


 No.172430

>>172427

>Poor kid is a junkie

weight lifting

NOT EVEN ONCE !!!


 No.172469

File: 1458450517635.jpg (568.02 KB, 1076x1100, 269:275, mithra_738.jpg)

facts:

generally better than placebo at reducing severe depression (pharma industry loves this)

better than placebo at increasing suicide in children (pharma industry hates this)

not technically addictive, but likely to form dependency and cause withdrawal if/when you stop

most of the patents expired in the 2000s, which made them cheap and widespread, but also means big business isn't really getting rich off the common ones anymore - prozac, zoloft, paxil, effexor, serzone iirc

>okay but I saw a study that said they were no better than placebo

Probably one of these two, they seem to be the ones most often mentioned in the news/alt media:

https://www.ncbi.nlm.nih.gov/pubmed/18303940

>2008 - meta-analysis of the clinical trials of four new SSRIs submitted to the FDA (luoxetine, venlafaxine, nefazodone, and paroxetine)

>These findings suggest that, compared with placebo, the new-generation antidepressants do not produce clinically significant improvements in depression in patients who initially have moderate or even very severe depression, but show significant effects only in the most severely depressed patients. The findings also show that the effect for these patients seems to be due to decreased responsiveness to placebo, rather than increased responsiveness to medication. Given these results, the researchers conclude that there is little reason to prescribe new-generation antidepressant medications to any but the most severely depressed patients unless alternative treatments have been ineffective.

https://jama.jamanetwork.com/article.aspx?articleid=185157

>2010 - meta-analysis of clinical trials submitted to the FDA (data from 6 studies with the same standards, 718 patients)

>The magnitude of benefit of antidepressant medication compared with placebo increases with severity of depression symptoms and may be minimal or nonexistent, on average, in patients with mild or moderate symptoms. For patients with very severe depression, the benefit of medications over placebo is substantial.

Full disclosure: I have been on an antidepressant in the past, following a head injury. It helped. Side effects were awful and I got off it asap. Therapy helped more than the drug.

I recommend you ask your doctor about any medical treatment rather than the internet.


 No.172535

>>172385

Been on some. Most felt more like a sedative than a 'feel happy' drug. Citalopram was the one they kept trying to get me on again and again but I'd refuse cos it actually increases your anxiety for the first six weeks until it kicks in.

I was even offered Lithium once, but I saw my mum on that. Basically a zombie.

>>172469

>Therapy helped more than the drug.

How socially awkward are you tho, LF? I get the picture therapy only works if you can open up to people in person to begin with


 No.172546

>>172540

y?


 No.172549

>>172548

lol'd. Good phrasing


 No.172563

File: 1458468807342-0.jpg (101.64 KB, 960x720, 4:3, slide_42.jpg)

File: 1458468807372-1.jpg (141.47 KB, 650x1026, 325:513, mithra_a83.jpg)

>>172535

>How socially awkward are you tho, LF?

Pretty awful, I'm one of those "you too" autists irl. Internet is easy because it's never face to face and rarely real time. Took me a while to open up.

>I'd refuse cos it actually increases your anxiety for the first six weeks until it kicks in.

Here's the funny thing - nobody really knows for sure the mechanism behind why SSRIs work. As an enzyme inhibitor, it should work pretty much right away, inhibiting reuptake and raising serotonin levels to make you happy, except it doesn't, it takes weeks to improve symptoms. The results are ass-backwards to the old "low serotonin chemical imbalance" idea. And putting a not-depressed person on a SSRI doesn't improve their mood.

http://bjp.rcpsych.org/content/195/2/102

>Blockade of transporters can be detected immediately after drug administration, whereas the therapeutic effect of antidepressant treatment requires a number of weeks to become clinically important.

>More recently attention has shifted to antidepressant-induced activation of second messengers and consequent changes in gene expression. This is associated with increased production of neurotropic factors resulting ultimately in changes in synaptic plasticity and neurogenesis.

So depression is something like when the brain's everyday growth is stalled by trauma or stress or whatever and struggling to form new connections, which is why your thoughts keep racing in circles even though you can't even get out of bed. And the new idea behind the medication is that the SSRI jump-starts this process, possibly because serotonin stimulates new neuron growth or growth factors associated with them. Problem is you can't really count neurons in the brain of a live subject…


 No.172567

>>172563

What about weed as an anti-depressant?


 No.172569

File: 1458470602086.jpg (906.77 KB, 1200x1600, 3:4, 1454035171292.jpg)

>>172567

Don't know a thing about it. Ask a scientist :3


 No.172571

>>172570

I guess, what kind of compensation is being offered?

no offense but I could do recordings for librevox if I wanted that kind of practice


 No.172573

>>172572

lol butthurt


 No.172574

File: 1458472863423.jpg (Spoiler Image, 213.24 KB, 850x1289, 850:1289, 1456159846125.jpg)

>>172572

>stop using surprise boxes too ffs you faggot

no


 No.172578

>>172567

Cannabis has been shown to improve depressive symptoms by stimulating the endocannabinoid system and increase neurogenesis, similar to the way many anti-depressants do but without the required daily regimen. Cannabis also has more mild side effects compared to many popular anti-depressants (including physical pain, trouble sleeping, fatigue and sexual dysfunction; not to mention potential birth defects if taken during pregnancy).

As long as the strain is correct and the dosage is accurate, marijuana can be a very effective treatment for stress, depression and anxiety by allowing the person to either focus on the situation objectively or by offering peace of mind enough to forget it for a while. In other words, Bob Marley was right; "When you smoke the herb, it reveals you to yourself". This can be hugely beneficial to those suffering from depression, and can be used in a hurry (by smoking for vaping the product) or be maintained throughout the day (with patches or edibles) the way one might take an antidepressant. Best of all, withdraw symptoms are comparatively minor and include irritability, problems with focus, and difficulty eating and sleeping.

Recent studies also indicate that cannabis can be an effective treatment for trauma-induced anxiety. One such study, published in the Journal of Psychopharmacology found that CBD (a non-psychoactive but extremely restorative cannabinoid) can help promote the extinction of learned fear responses. Those who suffer from Post-Traumatic Stress Disorder are, therefore, excellent candidates for therapy involving CBD.

http://archive.is/yNB4p

Marijuana use can have a range of mental health effects on people. Although rare, sometimes it can produce anxiety and panic in a person after a single use. In high doses, marijuana can cause confusion, thought disorder and hallucinations.

Some people are more vulnerable than others to experiencing these negative effects of marijuana, especially those with a personal or family history of mental illness. People who start using marijuana young, or use marijuana heavily, are more likely to experience psychotic disorders and depression later in life.

Doctors prescribe medication for depression, psychosis, bipolar affective disorder or schizophrenia to bring relief from the unpleasant symptoms that a patient may be experiencing. If that person continues to use marijuana while taking prescribed medications, unknown reactions can occur, which may make their condition worse. It also makes it very difficult for their doctor to prescribe the right drug at the right dose to improve their symptoms, as well as increasing the risk of non- compliance with medication regimes.

http://archive.is/pfpHr

Assorted pros and cons; http://medicalmarijuana.procon.org/view.answers.php?questionID=000226


 No.172609

they work for the most part but stopping taking them and thinking you can do just that is not the right idea lol




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