Remember the fundamentals: High tech and low life. It's just noir with drugs, computers and having watched a few episodes of Vice.
Sure, throw in whatever bleeding-edge technology and developing subcultural phenomenons you turn up in your research, but they're just trappings; story structure, pacing and characterisation are still what makes it work. The Difference Engine, which practically created Steampunk as a genre, was Gibson and Sterling testing the assertion that the Cyberpunk structure is viable, even when transplanted into Victoriana.