For some enlightenment comes from an experience. This could be drugs, or a life changing event. Siddhartha did not pursue spirituality until he left the comfort of his palace and has seen true suffering for the first time.
Then there are others like me. I have had no traumatic experience, I think something in my childhood simply made me question everything before accepting it. I remember my first epiphany with vivid detail, I even went into a bit of a panic attack. I was bored one summer day when I was about 12 or so. After cutting the grass I decided that neopets was just not entertaining me enough. I went for a walk around the neighborhood, and something just clicked. I had been depressed for sometime. I never really had a girlfriend and there was a societal pressure for me to obtain one. I was not happy with my family, I was not comforted by my friends. It was a low point, which looking back on was extremely selfish and ungrateful. Whatever lead me to this depression had me questioning everything. Why am I here? Why do we suffer? What's the purpose of humanity?
Then like a sack of bricks it hit me. We are not meant to live like this. The cars, the pavement, shitty over developed neighborhoods. This is not our natural state. Deviation from the natural state causes greater suffering because no matter what we have, we want more. We no longer have to fight everyday for shelter and food, so we find new problems to fight for. We get depressed because we don't get the car or job we want. When that's all they are - wants not needs. It sent me into one of the few panic attacks I ever had and when I calmed down I felt more grounded, more aware of the world around me. I started to notice more of the cause and effect relationship in the world. The pull and push, yin and yang - even if I did not realize it at the time. My short temper that afflicted me for most of my childhood seemed to have disappeared overnight.
I felt great. Though I had abandoned god a few years prior I felt a strange spiritual presence. It may have been nothing at all, but something lingered telling me there was more than just me. And yet, that's all there is - the self.