Does donating bone marrow or blood plasma have any negative effects on your own health? I'm not an expert, but it seems pretty logical to me that taking away stem cells that were supposed to be used by yourself can take a toll on you or at least have some negative effect in the long run. If you take away blood plasma, doesn't your body have to work harder to get the usual levels back? Wouldn't it effect your mortality rate by at least a tiny bit? I need some bucks, but I'm obsessed with living longer and being healthy.