>>6882>>6885Nice rephrasing. And you're talking about interesting ideas. Here are my two cents about it :
>Safari Zone saving feature removalYou can still include nods to the glitches related to it, like the Safari Zone pokes being catchable on the east coast of Cinnabar Island, in addition to using the fossil sprites of fossil Kabutops for Missingno.
>female protagonistIt was planned to have one on Red and Green, see the artworks about it. There might be sprites done about her, just find and use them.
>oddities in the battle systemNearly impossible unless heavily dedicated, but you can make changes to the moveset and the TMs, to fit better Gen 1.
>Mew glitchJust give the opportunity to meet a wild Mew the first time you reach the most known place to get it, on the switch from Lavender to Route 8. Bonus points if you manage to replicate how the glitch happens visually
>changes between Japanese Red/Green and American Red/BlueGoogle it. Sites like Gamefaqs and Serebii might have something like that. Avoid Bulbapedo like the plague it is, though.