I don't need help with systems since I plan on using a D&D 4e, Pathfinder, and some Homebrewed Rules mixed together.
What I really need help with are factions, nations, cities, populations, theme, minor quest, major story arcs, and gods (i.e. just about everything).
So far: I was thinking about setting it in a nation that has just fallen apart. Regional powers have been attempting to annex this peninsula nation by destabilizing it. Although successful, the regional nations have now gone to war with each other which has left this nation unclaimed by foreigners (Well, other than a few unaligned foreign warlords). The players will start in a prison fortress which has been left to ruin once the central authority fell to the destabilization. The prisoners took the advantage and rioted their way to freedom. In the process, the players have been set free to roam the land.
That's all I have, anyone willing to throw me a bone here?