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 No.144

Why are the types of gene segments that together code for the variable region of the light and heavy chain named V, J and V, D, J, respectively? I think J is named as such, because it joins V(D) with C. I know that CR1, CDR2 and CDR3 are parts of V, but CDR3 includes the whole D, if the chain is heavy, and J. So, why the names?

 No.145

File: 1436263624698.png (339.28 KB, 1097x1054, 1097:1054, antibody.png)

Also, I assume this pic is wrong, atleast it does not agree with the source, cited on the Wikipedia page for CDR.




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