I'm going to skip my other observations about the movie to focus on one broader theory that ties the entire film together. I've only seen the movie twice, and given it's length, somethings may not be entirely accurate so I'll need some additional viewings and feedback to tweak this further. This is still very rough and unpolished, so bear with me.
Let's take a short look back to the original film, Blade Runner, was the film actually about Deckard (Harrison Ford)? … was it about Rachel (Sean Young), or was it Roy Batty (Rutger Hauer) that stole the scenes and provide philosophical depth to the film?
So let's make the argument that Blade Runner 2049 is not even the story of K - he's a story telling medium, and in his own confusion as to whether he's key to the plot, also misleads the audience to believe the story is about him. If the story is not about K, then who is it about, Deckard? No, the first film wasn't about Deckard, and neither was this one. The stars of this film are the ladies, Luv, Joi, Mariette, Rachel, and the human Lt. "Madame" Joshi (K's boss).
Let's first examine the orphanage records that K discovers, two identical DNA records for a girl and a boy, the girl is listed as deceased from a fictional "Galatian's Syndrome." It's fictional, but why does it sound familiar?
>The Epistle to the Galatians, often shortened to Galatians, is the ninth book of the New Testament. It is a letter from Paul the Apostle to a number of Early Christian communities in Galatia.
>Galatians 5:22-23New International Version (NIV)
>22 But the fruit of the Spirit is love, joy, peace, forbearance, kindness, goodness, faithfulness, 23 gentleness and self-control. Against such things there is no law.
>The Fruit of the Holy Spirit is a biblical term that sums up nine attributes of a person or community living in accord with the Holy Spirit according to the Epistle to the Galatians: "But the fruit of the Spirit is love, joy, peace, patience, kindness, goodness, faithfulness, gentleness, and self-control." The fruits is contrasted with the works of the flesh which immediately precede it in the chapter.
>Catholic tradition follows the Vulgate version of Galatians in listing 12 fruits: charity, joy, peace, patience, benignity, goodness, longanimity, mildness, faith, modesty, continency, and chastity.
Interesting, two of our central characters (and competing love interests?) are Joi and Luv, and the "pleasure model" Mariette enables K's and Joi's act of love. In Hebrew, the name Mariette "is a Hebrew baby name. In Hebrew the meaning of the name Mariette is: Wished-for child; rebellion; bitter."
While in K's apartment, Mariette sees the wooden horse on the bedside table, picks it up flips it over revealing the 6.10.21 scribed on the bottom, and comments to herself as it was "from a dream," referencing that she shares at least one common memory implant with K. The "wished-for child" translation of her name may hold double meaning in that she shares the memory leading her to believe she might be the miracle child, or that she herself, may be another Rachel or vessel from a which another "wished-for child" may one day be born from. Mariette is a literal concubine in the story.
Does this suggest that Joi, Luv, and Mariette are all components to K's spirit? Madame also plays a motherly figure to K, but she also makes a point to note how fine he's done "without one" - "what's that?" - "a soul". Rachel also embodies many of these values, and her devine conception, she is the replicant equivalent to the virgin Mary, giving birth to a miracle child, a savior. Mary was also of Galilee.
… continued below.