I'll start with my own experiences, really hope to make this thread going so that more people get hyped and concider ditching their Xorg.
I use Parabola (Arch) with both gnome-shell and sway. I am not a fan of gnome-shell but currently use for reasons that are explained below. My hardware is an X240 (with removed wireless chip), that means Intel GPU. I've heard AMD GPUs should handle Wayland fine as well.
Positive:
Stability is great, in all the time I've been using it I had one single reproductible crash (more on that later).
To increase the amount of applications that run natively on Wayland, I have uninstalled gtk2. It only pulled out claws-mail and trayer, I can live with that. I'm not a fan of GNOME software, but they really did a good job making it work fine on Wayland, so I'm tolerating it. As file manager I use caja-gtk3, gnome-terminal as terminal. Most other GNOME apps run fine. Sometimes I run into segmentation faults but most of the time everything runs fine.
Negative:
I've had one crash. If connected to a VGA monitor/projector, on disconnecting the VGA cable from the computer, GNOME will kick me out of the session, disabling all extensions.
Unfortunately, some programs seem to have a much higher CPU usage than with Xorg. For example Pitivi and Glade (I develop GTK software so I definitely need it) make my fans spin up quite loudly.
My battery life also went down a little, probably related to my CPU heating up and the fans spinning up.
There doesn't seem to be a Wayland way of changing keyboard layouts yet (similar to configuring the InputClass in the Xorg.conf). GNOME supports it both in GDM and in the shell, but I haven't found a way to switch between layouts outside of GNOME (without completely exiting the session).
Other:
I'm still searching for a screen locker. GNOME has one built-in, I haven't tried using it outside of GNOME yet (would be great if that worked).
A GTK3 XMPP client (*not* Epiphany as it doesn't support any type of message encryption, piece of shit) would be great, both Pidgin and Gajim are GTK2 (while porting Pidgin to GTK3 is a WIP, Gajim is written in PyGTK and has to be ported to PyGObject, which will probably take a while).
Unfortunately most neat little window manager tools like dzen/lemonbar, trayer etc. are very Xorg-y.
Conclusion:
My experience is the following. If you mostly work in the browser and the terminal, there's not much that you will miss if you go full Wayland. If you are a GNOME 3 fan, most of your favourite applications are going to work just fine. If you edit videos, draw in GIMP or vectorize in Inkscape, things could get a little rough, but if you are willing to experience a few bugs, nothing is stopping you from using Wayland.
Pic slightly related, not my desktop but the default GNOME 3 image from GNOME's website.