To understand this show, you have to start with Yoko and Ayaya. They, being lesbians(genetic dead ends) and the most culturally Japanese characters of the show, represent the collective dead end that the Japanese people have become. Shino, who represents the average Japanese youth, is repulsed by this and is driven into the arms of the West, represented by Alice. Shino's love for Alice and all things English and Alice's love for Shino and all things Japanese represent Japan and the West's mutual love and fascination with each other, or at least each other's images. Shino's desire to become an interpreter despite her inability to speak English represents the simultaneous adoration and ignorance that the Japanese youth have of the West. Alice's small stature and sensitivity regarding her height represent the small nation of the U.K. constantly living in the shadow of the long gone British Empire. Her obsession with being the sole object of Shino's affection represents the West's fascination with the "exotic" Orient and it's subsequent desire to control it. And then there's Karen. Karen, being a hideous, smelly, repulsive, hapa who can speak neither English nor Japanese very well represents the rootless cultural abomination that comes from mixing the two cultures. Karen is every weaboo drawing on Deviant Art and every Japanese woman who becomes a Western-style roastie. She is multiculturalism incarnate. The ultimate message of Kiniro Mosaic is that the West and Japan must keep each other at arm's length no matter how much they desire each other. They must forever remain star crossed lovers so that multicultural horrors like Karen and Zach are kept at bay.